While getting ready for Halloween and searching for a skull left behind by Scream Street's first skeleton resident, Luke is recruited, along with his companions Resus and Cleo, to help the famous Headless Horseman find his stolen head.

Luke, Cleo, and Resus battle millions of spiders as they attempt to retrieve the heart of an ancient mummy, which is the third relic Luke needs to escape Scream Street and take his terrified parents home.

"Opening a doorway out of Scream Street seems to have brought with it a whole new set of problems--and now Luke, Resus, and Cleo are beginning to realize what they have unleashed. Scream Street faces a greater threat than ever before--normals!"--

With the sixth and final relic almost within his grasp, Luke learns something unexpected about the author who has been helping him in his quest to return with his terrified parents to his own world, presenting a dilemma that is not helped by a witch causing havoc in the neighborhood.

One week after arriving on Scream Street, Luke Watson is even more determined to find the six relics that will let him return home, but he and his friends must first face problems with the vampires' vital blood supply and with raging sewer rats.

Luke, Cleo, and Resus battle millions of spiders as they attempt to retrieve the heart of an ancient mummy, which is the third relic Luke needs to escape Scream Street and take his terrified parents home.

"Luke, Resus, and Cleo are eager to begin their new quest. First stop, Count Negatov's castle! As the three make their way through the bleak, murky wilds of Transylvania, it looks like this adventure will be dull, but easy. Until, that is, they are kidnapped by trolls"--Provided by publisher.

Luke, Resus, and Cleo are already on the trail of the second relic, a vial of witch's blood. But obstacles abound-first the evil Sir Otto Sneer turns off the blood supply, then a swarm of vampire rodents escapes and now all the residents have been infected with vampire Energy! It looks as if Luke and his friends will have to choose between finding the relic and saving their neighbors...